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GATA2 anticorps (N-Term)

GATA2 Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2777458
  • Antigène Voir toutes GATA2 Anticorps
    GATA2 (GATA Binding Protein 2 (GATA2))
    Épitope
    • 25
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 78
    • 34
    • 23
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval
    Hôte
    • 76
    • 3
    Lapin
    Clonalité
    • 74
    • 5
    Polyclonal
    Conjugué
    • 37
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp GATA2 est non-conjugé
    Application
    • 61
    • 20
    • 13
    • 13
    • 10
    • 7
    • 7
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    PYYANPAHAR ARVSYSPAHA RLTGGQMCRP HLLHSPGLPW LDGGKAALSA
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against GATA2. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human GATA2
    Top Product
    Discover our top product GATA2 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 480 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Wang, Zhu, Guo, Dong, Liu, Yin, Zhang, Li, Liu, Ma, Song, He, Wang, Wang, Zhang, Li, Yu: "A regulatory circuit comprising GATA1/2 switch and microRNA-27a/24 promotes erythropoiesis." dans: Nucleic acids research, Vol. 42, Issue 1, pp. 442-57, (2013) (PubMed).

    Fujiwara, Yokoyama, Okitsu, Kamata, Fukuhara, Onishi, Fujimaki, Takahashi, Ishizawa, Bresnick, Harigae: "Gene expression profiling identifies HOXB4 as a direct downstream target of GATA-2 in human CD34+ hematopoietic cells." dans: PLoS ONE, Vol. 7, Issue 9, pp. e40959, (2012) (PubMed).

    Jack, Crossley: "GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis." dans: The Journal of biological chemistry, Vol. 285, Issue 42, pp. 32405-14, (2010) (PubMed).

    Huang, Niu, Liu, Wang, Sturgis, Wei: "The functional IGFBP7 promoter -418G>A polymorphism and risk of head and neck cancer." dans: Mutation research, Vol. 702, Issue 1, pp. 32-9, (2010) (PubMed).

    Mammoto, Connor, Mammoto, Yung, Huh, Aderman, Mostoslavsky, Smith, Ingber: "A mechanosensitive transcriptional mechanism that controls angiogenesis." dans: Nature, Vol. 457, Issue 7233, pp. 1103-8, (2009) (PubMed).

    Tsuzuki, Kitajima, Nakano, Glasow, Zelent, Enver: "Cross talk between retinoic acid signaling and transcription factor GATA-2." dans: Molecular and cellular biology, Vol. 24, Issue 15, pp. 6824-36, (2004) (PubMed).

  • Antigène
    GATA2 (GATA Binding Protein 2 (GATA2))
    Autre désignation
    GATA2 (GATA2 Produits)
    Synonymes
    anticorps DCML, anticorps MONOMAC, anticorps NFE1B, anticorps Gata-2, anticorps xgata-2, anticorps xgata2, anticorps GATA-2, anticorps NF-E1b, anticorps GATA2, anticorps Gata2, anticorps gata2, anticorps zg2, anticorps zgc:91840, anticorps GATA binding protein 2, anticorps GATA binding protein 2 L homeolog, anticorps amidase, anticorps glutamyl/aspartyl-tRNA(Gln/Asp) amidotransferasesubunit A, anticorps hypothetical protein, anticorps glutamyl-tRNA(Gln) amidotransferase, subunit GatA (Glu-ADT subunit A), anticorps GATA2 transcription factor, anticorps putative gata binding factor, anticorps GATA binding protein 2a, anticorps GATA binding protein 2b, anticorps GATA2, anticorps Gata2, anticorps gata2.L, anticorps RR_RS20245, anticorps gatA2, anticorps Smp_018590, anticorps gata2a, anticorps gata2b
    Sujet
    The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells is essential for normal primitive and definitive erythropoiesis and is expressed at high levels in erythroid cells, mast cells, and megakaryocytes. GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells.
    Alias Symbols: DCML, NFE1B, MONOMAC
    Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-9, KRT40, PRR20A, ADAMTSL4, TRAF1, PSMA3, MDFI, GOLGA2, FHL3, TRIM23, AKT1, BMI1, SPI1, SMAD4, ELAVL1, KAT2A, EP300, MED1, POU1F1, POU2AF1, ZBTB32, ZFPM1, ZBTB16, HDAC5, HDAC3, HHEX, RARA, RXRA, MAPK1, JUN, CEBPA, STAT3, PML,
    Protein Size: 480
    Poids moléculaire
    50 kDa
    ID gène
    2624
    NCBI Accession
    NM_032638, NP_116027
    UniProt
    P23769
    Pathways
    Stem Cell Maintenance
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