DREAM anticorps (N-Term)

N° du produit ABIN2777506

L’anticorps Lapin Polyclonal anti-DREAM a été validé pour WB et IHC. Il convient pour détecter DREAM dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Cobaye, Lapin, Poisson zèbre (Danio rerio) et Porc. Il y a 1 publication disponible.

Aperçu rapide pour DREAM anticorps (N-Term) (ABIN2777506)

Antigène: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Cobaye, Lapin, Poisson zèbre (Danio rerio), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DREAM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-DREAM anticorps

Épitope: N-Term

Séquence: STVRHQPEGL DQLQAQTKFT KKELQSLYRG FKNECPTGLV DEDTFKLIYA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against CSEN. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CSEN

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 256 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-DREAM (ABIN2777506)

Fernandes, Ribeiro, Martínez, Orensanz, Barahona, Martínez-Sáenz, Recio, Benedito, Bustamante, Carballido, García-Sacristán, Prieto, Hernández: "Endogenous hydrogen sulfide has a powerful role in inhibitory neurotransmission to the pig bladder neck." dans: The Journal of urology, Vol. 189, Issue 4, pp. 1567-73, (2013) (PubMed).

Détails sur DREAM

Antigène: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Autre désignation: CSEN

Sujet: CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.
Alias Symbols: CSEN, DREAM, KCHIP3
Protein Interaction Partner: MAVS, CD177, IGLV3-25, IL6ST, IGF1R, KCND2, CLN3, CALM2, KCNIP3, PPP3CA, GRK6, ADRBK1, UBE2I, UBC, PCBD2, TARBP2, PSEN2, CASP3, CREM, CREB1, PSEN1, CRK,
Protein Size: 256

Poids moléculaire: 29 kDa

ID gène: 30818

NCBI Accession: NM_013434, NP_038462

UniProt: Q9Y2W7