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DREAM anticorps (N-Term)

KCNIP3 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Cobaye, Lapin, Poisson zèbre (Danio rerio), Porc WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2777506
  • Antigène Voir toutes DREAM (KCNIP3) Anticorps
    DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
    Épitope
    • 10
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 55
    • 31
    • 20
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Cobaye, Lapin, Poisson zèbre (Danio rerio), Porc
    Hôte
    • 48
    • 6
    • 2
    Lapin
    Clonalité
    • 53
    • 3
    Polyclonal
    Conjugué
    • 28
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DREAM est non-conjugé
    Application
    • 51
    • 26
    • 21
    • 13
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    STVRHQPEGL DQLQAQTKFT KKELQSLYRG FKNECPTGLV DEDTFKLIYA
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
    Attributs du produit
    This is a rabbit polyclonal antibody against CSEN. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human CSEN
    Top Product
    Discover our top product KCNIP3 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 256 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Fernandes, Ribeiro, Martínez, Orensanz, Barahona, Martínez-Sáenz, Recio, Benedito, Bustamante, Carballido, García-Sacristán, Prieto, Hernández: "Endogenous hydrogen sulfide has a powerful role in inhibitory neurotransmission to the pig bladder neck." dans: The Journal of urology, Vol. 189, Issue 4, pp. 1567-73, (2013) (PubMed).

  • Antigène
    DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
    Autre désignation
    CSEN (KCNIP3 Produits)
    Synonymes
    anticorps CSEN, anticorps DREAM, anticorps KCHIP3, anticorps 4933407H12Rik, anticorps AI413860, anticorps Csen, anticorps KChIP3, anticorps R74849, anticorps Dream, anticorps rKChIP3, anticorps csen, anticorps im:7145308, anticorps kcnip3, anticorps zgc:73306, anticorps KCNIP3, anticorps potassium voltage-gated channel interacting protein 3, anticorps Kv channel-interacting protein 4, anticorps calsenilin, anticorps Kv channel interacting protein 3, calsenilin, anticorps Kv channel interacting protein 3b, calsenilin, anticorps KCNIP3, anticorps LOC5568664, anticorps CpipJ_CPIJ002549, anticorps Tsp_05009, anticorps Kcnip3, anticorps kcnip3b, anticorps kcnip3
    Sujet
    CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.
    Alias Symbols: CSEN, DREAM, KCHIP3
    Protein Interaction Partner: MAVS, CD177, IGLV3-25, IL6ST, IGF1R, KCND2, CLN3, CALM2, KCNIP3, PPP3CA, GRK6, ADRBK1, UBE2I, UBC, PCBD2, TARBP2, PSEN2, CASP3, CREM, CREB1, PSEN1, CRK,
    Protein Size: 256
    Poids moléculaire
    29 kDa
    ID gène
    30818
    NCBI Accession
    NM_013434, NP_038462
    UniProt
    Q9Y2W7
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