HIC1 anticorps (N-Term)

N° du produit ABIN2777507

Cet anticorps Lapin Polyclonal détecte spécifiquement HIC1 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Cobaye, Chien, Boeuf (Vache) et Porc.Il a été cité dans 1 publication.

Aperçu rapide pour HIC1 anticorps (N-Term) (ABIN2777507)

Antigène: HIC1 (Hypermethylated in Cancer 1 (HIC1))

Reactivité: Humain, Rat, Souris, Cobaye, Chien, Boeuf (Vache), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIC1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HIC1 anticorps

Épitope: N-Term

Fonction: HIC1 Antibody - N-terminal region

Séquence: RRCSPLCGLD LSKKSPPGSA APERPLAERE LPPRPDSPPS AGPAAYKEPP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 85%, Pig: 100%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against HIC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HIC1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31936-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HIC1 (ABIN2777507)

Stöcklein, Smardova, Macak, Katzenberger, Höller, Wessendorf, Hutter, Dreyling, Haralambieva, Mäder, Müller-Hermelink, Rosenwald, Ott, Kalla: "Detailed mapping of chromosome 17p deletions reveals HIC1 as a novel tumor suppressor gene candidate telomeric to TP53 in diffuse large B-cell lymphoma." dans: Oncogene, Vol. 27, Issue 18, pp. 2613-25, (2008) (PubMed).

Détails sur HIC1

Antigène: HIC1 (Hypermethylated in Cancer 1 (HIC1))

Autre désignation: HIC1

Sujet:

Background Information: HIC1 is a transcriptional repressor. HIC1 may act as a tumor suppressor. HIC1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIC1 may be a cause of the facial dysmorphism and additional birth defects (except for liss

Gene Name: Hypermethylated in cancer 1

Alternative Symbols: hic-1, ZBTB29, ZNF901

Protein Name: Hypermethylated in cancer 1 protein

Poids moléculaire: 74kDa

ID gène: 3090

NCBI Accession: NP_006488

UniProt: Q14526

Pathways: Positive Regulation of Response to DNA Damage Stimulus