PAWR anticorps (Middle Region)

N° du produit ABIN2777555

Détail du produit anti-PAWR anticorps

Antigène: PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAWR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: SYLLQEPPRT VSGRYKSTTS VSEEDVSSRY SRTDRSGFPR YNRDANVSGT

Homologie: Dog: 100%, Horse: 85%, Human: 100%, Mouse: 91%, Rabbit: 77%, Rat: 91%

Attributs du produit: This is a rabbit polyclonal antibody against PAWR. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PAWR

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 340 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PAWR

Antigène: PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

Autre désignation: PAWR (PAWR Produits)

Synonymes: anticorps MGC81382, anticorps pawrl, anticorps zgc:103513, anticorps PAWR, anticorps PAR4, anticorps Par-4, anticorps Par4, anticorps 2310001G03Rik, anticorps pro-apoptotic WT1 regulator, anticorps PRKC, apoptosis, WT1, regulator L homeolog, anticorps PRKC, apoptosis, WT1, regulator, anticorps PAWR, anticorps pawr.L, anticorps pawr, anticorps Pawr

Sujet: The tumor suppressor WT1 represses and activates transcription. Anti-Prostate Apoptosis Response Protein Par-4 (PAWR) is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.
Alias Symbols: PAR4, Par-4
Protein Interaction Partner: FBXO45, UBC, EED, FAM129B, SNX6, CAND1, VPS29, JMJD6, STAT1, SNX2, SHMT2, SHMT1, PPM1G, IDE, H3F3A, CARS, ATP6V1C1, APEH, PAN2, DRD2, DAPK3, SQSTM1, PRKCZ, Spsb4, Spsb2, SPSB1, FBXO25, HSPA5, Cep350, Kif23, THAP1, SLC5A7, AATF, TFPT, PAWR, WT1, RRAS2, ATP
Protein Size: 340

Poids moléculaire: 37 kDa

ID gène: 5074

NCBI Accession: NM_002583, NP_002574

UniProt: O75796