PAX7 anticorps (C-Term)

N° du produit ABIN2777560

Il existe 6+ publications pour ce produit. L’anticorps anti-PAX7 Polyclonal Lapin est utilisé pour la détection de PAX7 dans des échantillons de Humain, Souris, Rat, Chien, Cobaye, Boeuf (Vache), Lapin et Cheval. Il a été validé pour WB et IHC.

Aperçu rapide pour PAX7 anticorps (C-Term) (ABIN2777560)

Antigène: PAX7 (Paired Box 7 (PAX7))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Boeuf (Vache), Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAX7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PAX7 anticorps

Épitope: C-Term

Fonction: PAX7 Antibody - C-terminal region

Séquence: QADFSISPLH GGLDSATSIS ASCSQRADSI KPGDSLPTSQ AYCPPTYSTT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against PAX7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of PAX7

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8107552

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PAX7 (ABIN2777560)

Gautam, Nirwane, Yao: "Laminin differentially regulates the stemness of type I and type II pericytes." dans: Stem cell research & therapy, Vol. 8, Issue 1, pp. 28, (2017) (PubMed).

Czerwinska, Nowacka, Aszer, Gawrzak, Archacka, Fogtman, Iwanicka-Nowicka, Jańczyk-Ilach, Koblowska, Ciemerych, Grabowska: "Cell cycle regulation of embryonic stem cells and mouse embryonic fibroblasts lacking functional Pax7." dans: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 21, pp. 2931-2942, (2016) (PubMed).

Wehling-Henricks, Li, Lindsey, Wang, Welc, Ramos, Khanlou, Kuro-O, Tidball: "Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy." dans: Human molecular genetics, Vol. 25, Issue 12, pp. 2465-2482, (2016) (PubMed).

Akahori, Karmali, Polavarapu, Lyle, Weiss, Shin, Husain, Naqvi, Van Dam, Habib, Choi, King, Pachura, Taylor, Lefer, Finn: "CD163 interacts with TWEAK to regulate tissue regeneration after ischaemic injury." dans: Nature communications, Vol. 6, pp. 7792, (2015) (PubMed).

McDonald, Hebert, McLoon: "Sparing of the extraocular muscles in mdx mice with absent or reduced utrophin expression: A life span analysis." dans: Neuromuscular disorders : NMD, Vol. 25, Issue 11, pp. 873-87, (2015) (PubMed).

Caldow, Thomas, Dale, Tomkinson, Buckley, Cameron-Smith: "Early myogenic responses to acute exercise before and after resistance training in young men." dans: Physiological reports, Vol. 3, Issue 9, (2015) (PubMed).

Détails sur PAX7

Antigène: PAX7 (Paired Box 7 (PAX7))

Autre désignation: PAX7

Sujet:

Background Information: PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box gene 7 is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.

Gene Name: Paired box 7

Alternative Symbols: HUP1, RMS2, PAX7B, MYOSCO

Protein Name: Paired box protein Pax-7

Poids moléculaire: 57kDa

ID gène: 5081

NCBI Accession: NP_002575

UniProt: P23759