MXD4 anticorps (N-Term)
Aperçu rapide pour MXD4 anticorps (N-Term) (ABIN2777585)
Antigène
Voir toutes MXD4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- SLLILLEAAE YLERRDREAE HGYASVLPFD GDFAREKTKA AGLVRKAPNN
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Sheep: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against MXD4. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human MXD4
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 209 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MXD4 (MAX Dimerization Protein 4 (MXD4))
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Autre désignation
- MXD4
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Sujet
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MXD4 is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
Alias Symbols: MAD4, MST149, MSTP149, bHLHc12
Protein Interaction Partner: TCP10L, UBC, SHBG, SIN3A, MLX, MAX, SMC3,
Protein Size: 209 -
Poids moléculaire
- 24 kDa
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ID gène
- 10608
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NCBI Accession
- NM_006454, NP_006445
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UniProt
- Q14582
Antigène
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