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ACSL1 anticorps (N-Term)

Cet anticorps anti-ACSL1 est un anticorps Lapin Polyclonal détectant ACSL1 dans WB et IHC. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Chien, Poisson zèbre (Danio rerio), Porc et Lapin. Ce Primary Antibody a été cité dans 1 publication.
N° du produit ABIN2777591

Aperçu rapide pour ACSL1 anticorps (N-Term) (ABIN2777591)

Antigène

Voir toutes ACSL1 (Acsl1) Anticorps
ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Reactivité

  • 27
  • 11
  • 9
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Chien, Poisson zèbre (Danio rerio), Porc, Lapin

Hôte

  • 28
  • 1
Lapin

Clonalité

  • 28
  • 1
Polyclonal

Conjugué

  • 22
  • 3
  • 1
  • 1
  • 1
  • 1
Cet anticorp ACSL1 est non-conjugé

Application

  • 24
  • 15
  • 8
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Épitope

    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    N-Term

    Séquence

    ALLDSDEPLV YFYDDVTTLY EGFQRGIQVS NNGPCLGSRK PDQPYEWLSY

    Homologie

    Cow: 85%, Dog: 92%, Guinea Pig: 85%, Horse: 79%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 100%, Rat: 85%, Zebrafish: 77%

    Attributs du produit

    This is a rabbit polyclonal antibody against ACSL1. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N terminal region of human ACSL1
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 698 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Soupene, Kuypers: "Multiple erythroid isoforms of human long-chain acyl-CoA synthetases are produced by switch of the fatty acid gate domains." dans: BMC molecular biology, Vol. 7, pp. 21, (2006) (PubMed).

  • Antigène

    ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

    Autre désignation

    ACSL1

    Sujet

    ACSL1 encodes an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation.The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ACS1, FACL1, FACL2, LACS, LACS1, LACS2
    Protein Interaction Partner: SUMO2, PARK2, ATP4A, UBC, NR3C2, ECT2, UBD,
    Protein Size: 698

    Poids moléculaire

    78 kDa

    ID gène

    2180

    NCBI Accession

    NM_001995, NP_001986

    UniProt

    P33121

    Pathways

    Regulation of Lipid Metabolism by PPARalpha
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