HES6 anticorps (Middle Region)

N° du produit ABIN2777652

Cet anticorps Lapin Polyclonal détecte spécifiquement HES6 dans WB. Il présente une réactivité envers Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour HES6 anticorps (Middle Region) (ABIN2777652)

Antigène: HES6 (Hairy and Enhancer of Split 6 (HES6))

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HES6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HES6 anticorps

Épitope: Middle Region

Séquence: LLAGTEVQAK LENAEVLELT VRRVQGALRG RAREREQLQA EASERFAAGY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 75%, Human: 100%, Mouse: 100%, Rabbit: 75%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against Hes6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Mouse Hes6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 224 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HES6

Antigène: HES6 (Hairy and Enhancer of Split 6 (HES6))

Autre désignation: Hes6

Sujet: Hes6 does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Hes6 also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. It promotes cell differentiation.
Alias Symbols: AI326893, bHLHb41
Protein Interaction Partner: Tle1, Tef, Mycn, Ssbp3, Hes1,
Protein Size: 224

Poids moléculaire: 24 kDa

ID gène: 55927

NCBI Accession: NM_019479, NP_062352

UniProt: Q9JHE6