HES6 anticorps (Middle Region)
Aperçu rapide pour HES6 anticorps (Middle Region) (ABIN2777652)
Antigène
Voir toutes HES6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- Hes6 Antibody - middle region
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Séquence
- LLAGTEVQAK LENAEVLELT VRRVQGALRG RAREREQLQA EASERFAAGY
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 75%, Human: 100%, Mouse: 100%, Rabbit: 75%, Rat: 100%, Zebrafish: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against Hes6. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Mouse Hes6
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32897-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- HES6 (Hairy and Enhancer of Split 6 (HES6))
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Autre désignation
- Hes6
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Sujet
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Background Information: Hes6 does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Hes6 also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. It promotes cell differentiation.
Alternative Symbols: bHLHb4, bHLHb41, AI326893
Protein Name: Transcription cofactor HES-6
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Poids moléculaire
- 24kDa
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ID gène
- 55927
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NCBI Accession
- NP_062352
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UniProt
- Q9JHE6
Antigène
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