HES6 anticorps (Middle Region)

N° du produit ABIN2777652

Détail du produit anti-HES6 anticorps

Antigène: HES6 (Hairy and Enhancer of Split 6 (HES6))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Chien, Cobaye, Boeuf (Vache), Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HES6 est non-conjugé

Application: Western Blotting (WB)

Séquence: LLAGTEVQAK LENAEVLELT VRRVQGALRG RAREREQLQA EASERFAAGY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 75%, Human: 100%, Mouse: 100%, Rabbit: 75%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against Hes6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Mouse Hes6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 224 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HES6

Antigène: HES6 (Hairy and Enhancer of Split 6 (HES6))

Autre désignation: Hes6 (HES6 Produits)

Synonymes: anticorps YF-30, anticorps her13.2, anticorps AI326893, anticorps bHLHb41, anticorps HES-6, anticorps bHLHc23, anticorps hes family bHLH transcription factor 6, anticorps hairy and enhancer of split 6, anticorps hes6, anticorps Hes6, anticorps HES6

Sujet: Hes6 does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Hes6 also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. It promotes cell differentiation.
Alias Symbols: AI326893, bHLHb41
Protein Interaction Partner: Tle1, Tef, Mycn, Ssbp3, Hes1,
Protein Size: 224

Poids moléculaire: 24 kDa

ID gène: 55927

NCBI Accession: NM_019479, NP_062352

UniProt: Q9JHE6