TDP2 anticorps (Middle Region)
Aperçu rapide pour TDP2 anticorps (Middle Region) (ABIN2777707)
Antigène
Voir toutes TDP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- TTRAP Antibody - middle region
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Séquence
- IPPYYSYLKK RSSNYEIITG HEEGYFTAIM LKKSRVKLKS QEIIPFPSTK
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against TTRAP. It was validated on Western Blot and immunohistochemistry.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human TTRAP
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8115094
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "TTRAP is a novel PML nuclear bodies-associated protein." dans: Biochemical and biophysical research communications, Vol. 375, Issue 3, pp. 395-8, (2008) (PubMed).
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- TDP2 (tyrosyl-DNA phosphodiesterase 2 (TDP2))
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Autre désignation
- TTRAP
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Sujet
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Background Information: The TTRAP gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
Gene Name: Tyrosyl-DNA phosphodiesterase 2
Alternative Symbols: EAP2, AD022, EAPII, TTRAP, hTDP2, dJ30M3.3
Protein Name: Tyrosyl-DNA phosphodiesterase 2
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Poids moléculaire
- 41kDa
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ID gène
- 51567
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NCBI Accession
- NP_057698
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UniProt
- O95551
Antigène
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