Endoglin anticorps (N-Term)

N° du produit ABIN2777735

Cet anticorps Lapin Polyclonal détecte spécifiquement Endoglin dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat et Cobaye.

Aperçu rapide pour Endoglin anticorps (N-Term) (ABIN2777735)

Antigène: Endoglin (ENG)

Reactivité: Humain, Souris, Rat, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Endoglin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Endoglin anticorps

Épitope: N-Term

Séquence: ILEVHVLFLE FPTGPSQLEL TLQASKQNGT WPREVLLVLS VNSSVFLHLQ

Homologie: Guinea Pig: 91%, Human: 100%, Mouse: 91%, Rat: 91%

Attributs du produit: This is a rabbit polyclonal antibody against ENG. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ENG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 625 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Endoglin

Antigène: Endoglin (ENG)

Autre désignation: ENG

Sujet: Endoglin is a homodimeric transmembrane glycoprotein highly expressed by endothelial cells. It is a component of the transforming growth factor beta receptor complex since it binds TGFB1 and TGFB3 with high affinity. Mutations in the endoglin gene produce hereditary hemorrhagic telangiectasia.
Alias Symbols: END, ORW, HHT1, ORW1, CD105
Protein Interaction Partner: ENG, TGFBR2, TGFBR1, TGFB3, TGFB1, ACVRL1, TUFM, TCTEX1D4, TGFBR3, TGFB2, INHBA, BMP7, BMP2, ACVR2A, ACVR1, ACVR2B,
Protein Size: 625

Poids moléculaire: 68 kDa

ID gène: 2022

NCBI Accession: NM_000118, NP_000109

UniProt: P17813