HS3ST1 anticorps (Middle Region)

N° du produit ABIN2777744

Cet anticorps Lapin Polyclonal détecte spécifiquement HS3ST1 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Cobaye et Lapin.

Aperçu rapide pour HS3ST1 anticorps (Middle Region) (ABIN2777744)

Antigène: HS3ST1 (Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 1 (HS3ST1))

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HS3ST1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HS3ST1 anticorps

Épitope: Middle Region

Séquence: TKGFYCLRDS GRDRCLHESK GRAHPQVDPK LLNKLHEYFH EPNKKFFELV

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against HS3ST1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human HS3ST1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 307 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HS3ST1

Antigène: HS3ST1 (Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 1 (HS3ST1))

Autre désignation: HS3ST1

Sujet: HS3ST1 is the rate limiting enzyme for synthesis of HSact. HS3ST1 performs the crucial step modification in the biosynthesis of anticoagulant heparan sulfate (HSact) that is to complete the structure of the antithrombin pentasaccharide binding site.Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It possesses both heparan sulfate glucosaminyl 3-O-sulfotransferase activity, anticoagulant heparan sulfate conversion activity, and is a rate limiting enzyme for synthesis of anticoagulant heparan. This enzyme is an intraluminal Golgi resident protein.
Alias Symbols: 3OST, 3OST1
Protein Interaction Partner: LGR4, APP, UBC,
Protein Size: 307

Poids moléculaire: 34 kDa

ID gène: 9957

NCBI Accession: NM_005114, NP_005105

UniProt: O14792

Pathways: Glycosaminoglycan Metabolic Process