MAP4K5 anticorps (Middle Region)

N° du produit ABIN2777750

Cet anticorps anti-MAP4K5 est un anticorps Lapin Polyclonal détectant MAP4K5 dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio) et Saccharomyces cerevisiae.

Aperçu rapide pour MAP4K5 anticorps (Middle Region) (ABIN2777750)

Antigène: MAP4K5 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP4K5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAP4K5 anticorps

Épitope: Middle Region

Séquence: QGKSFKSDEV TQEISDETRV FRLLGSDRVV VLESRPTENP TAHSNLYILA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against MAP4K5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MAP4K5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 846 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MAP4K5

Antigène: MAP4K5 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5))

Autre désignation: MAP4K5

Sujet: MAP4K5 may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
Alias Symbols: GCKR, KHS, KHS1, MAPKKKK5
Protein Interaction Partner: CRK, ELAVL1, UBC, NEDD4, SETDB1, ZNF440, COPS5, HCK, GRB2, TANK, CRKL, TRAF2, ABL1, BCR,
Protein Size: 846

Poids moléculaire: 95 kDa

ID gène: 11183

NCBI Accession: NM_006575, NP_006566

UniProt: Q9Y4K4