MAP4K5 anticorps (Middle Region)
Aperçu rapide pour MAP4K5 anticorps (Middle Region) (ABIN2777750)
Antigène
Voir toutes MAP4K5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Middle Region
-
Fonction
- MAP4K5 Antibody - middle region
-
Séquence
- QGKSFKSDEV TQEISDETRV FRLLGSDRVV VLESRPTENP TAHSNLYILA
-
Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%, Zebrafish: 86%
-
Attributs du produit
- This is a rabbit polyclonal antibody against MAP4K5. It was validated on Western Blot using a cell lysate as a positive control.
-
Purification
- Affinity Purified
-
Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human MAP4K5
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Commentaires
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33101-100UG
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.5 mg/mL
-
Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- prevent freeze-thaw cycles
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- MAP4K5 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5))
-
Autre désignation
- MAP4K5
-
Sujet
-
Background Information: MAP4K5 may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
Gene Name: Mitogen-activated protein kinase kinase kinase kinase 5
Alternative Symbols: KHS, GCKR, KHS1, MAPKKKK5
Protein Name: Mitogen-activated protein kinase kinase kinase kinase 5
-
Poids moléculaire
- 95kDa
-
ID gène
- 11183
-
NCBI Accession
- NP_006566
-
UniProt
- Q9Y4K4
Antigène
-