SOX6 anticorps (Middle Region)

N° du produit ABIN2777776

Détail du produit anti-SOX6 anticorps

Antigène: SOX6 (SRY (Sex Determining Region Y)-Box 6 (SOX6))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOX6 est non-conjugé

Application: Western Blotting (WB)

Séquence: YGMKTDGGSL AGNEMINGED EMEMYDDYED DPKSDYSSEN EAPEAVSAN

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SOX6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SOX6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 804 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SOX6

Antigène: SOX6 (SRY (Sex Determining Region Y)-Box 6 (SOX6))

Autre désignation: SOX6 (SOX6 Produits)

Synonymes: anticorps HSSOX6, anticorps SOXD, anticorps Sox6, anticorps AI987981, anticorps SOX-LZ, anticorps fc35a10, anticorps fc50e03, anticorps sox-lz, anticorps sox6b, anticorps wu:fc35a10, anticorps wu:fc50e03, anticorps SRY-box 6, anticorps SRY box 6, anticorps SRY (sex determining region Y)-box 6, anticorps SOX6, anticorps Sox6, anticorps sox6

Sujet: SOX6 is a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. SOX6 is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. SOX6 interacts with other family members to cooperatively activate gene expression.Members of the SOX gene family, such as SOX6, encode transcription factors defined by the conserved high mobility group (HMG) DNA-binding domain. Unlike most transcription factors, SOX transcription factors bind to the minor groove of DNA, causing a 70- to 85-degree bend and introducing local conformational changes (Cohen-Barak et al., 2001 [PubMed 11255018]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2696 AL136780.1 1-2696 2697-5158 AC009869.7 10394-12855
Alias Symbols: HSSOX6, SOXD
Protein Interaction Partner: TAF4, TRIP12, UBC, SOX2, POMGNT1, ZNF184, UBE2J1, SUMO1, SUMO2, SUMO3, HDAC1, CTNNB1, SOX5, CENPK, DAZAP2, SOX6, CTBP2,
Protein Size: 804

Poids moléculaire: 89 kDa

ID gène: 55553

NCBI Accession: NM_017508, NP_059978

UniProt: A8MRT1