MTA3 anticorps (N-Term)

N° du produit ABIN2777793

Détail du produit anti-MTA3 anticorps

Antigène: MTA3 (Metastasis Associated 1 Family, Member 3 (MTA3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTA3 est non-conjugé

Application: Western Blotting (WB)

Séquence: TLIMLADKHA KEIEEESETT VEADLTDKQK HQLKHRELFL SRQYESLPAT

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MTA3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of human MTA1

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MTA3

Antigène: MTA3 (Metastasis Associated 1 Family, Member 3 (MTA3))

Autre désignation: MTA3 (MTA3 Produits)

Synonymes: anticorps MTA3, anticorps DKFZp468E247, anticorps fj99h01, anticorps mta1, anticorps wu:fj99h01, anticorps zgc:56396, anticorps 1110002J22Rik, anticorps mKIAA1266, anticorps metastasis associated 1 family member 3, anticorps metastasis associated 1 family, member 3, anticorps metastasis associated 3, anticorps MTA3, anticorps Mta3, anticorps mta3

Sujet: This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene.
Protein Size: 392

Poids moléculaire: 43 kDa

ID gène: 9112

NCBI Accession: NM_001203258, NP_001190187

Pathways: Chromatin Binding