RFXAP anticorps (Middle Region)

N° du produit ABIN2777814

Détail du produit anti-RFXAP anticorps

Antigène: RFXAP (Regulatory Factor X-Associated Protein (RFXAP))

Épitope: Middle Region

Reactivité: Humain, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFXAP est non-conjugé

Application: Western Blotting (WB)

Séquence: SDQALNCGGT ASTGSAGNVK LEESADNILS IVKQRTGSFG DRPARPTLLE

Homologie: Guinea Pig: 100%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RFXAP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RFXAP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 272 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RFXAP

Antigène: RFXAP (Regulatory Factor X-Associated Protein (RFXAP))

Autre désignation: RFXAP (RFXAP Produits)

Sujet: RFXAP is part of the RFX complex that binds to the X-box of MHC II promoters.Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: EPS8, NHP2L1, NCL, MLLT1, HDAC4, SMARCA4, RFXANK, RFX5,
Protein Size: 272

Poids moléculaire: 28 kDa

ID gène: 5994

NCBI Accession: NM_000538, NP_000529

UniProt: O00287