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PRDM16 anticorps (Middle Region)

PRDM16 Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Boeuf (Vache), Porc WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2777828
  • Antigène Voir toutes PRDM16 Anticorps
    PRDM16 (PR Domain Containing 16 (PRDM16))
    Épitope
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    Humain, Souris, Rat, Chien, Cobaye, Cheval, Boeuf (Vache), Porc
    Hôte
    • 14
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 16
    • 2
    Polyclonal
    Conjugué
    • 14
    • 2
    • 1
    • 1
    Cet anticorp PRDM16 est non-conjugé
    Application
    • 12
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    LNHTQDAKLP SPLGNPALPL VSAVSNSSQG TTAAAGPEEK FESRLEDSCV
    Homologie
    Cow: 92%, Dog: 77%, Guinea Pig: 86%, Horse: 85%, Human: 100%, Mouse: 79%, Pig: 92%, Rat: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against PRDM16. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human PRDM16
    Top Product
    Discover our top product PRDM16 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 1275 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    PRDM16 (PR Domain Containing 16 (PRDM16))
    Autre désignation
    PRDM16 (PRDM16 Produits)
    Synonymes
    anticorps PRDM16, anticorps wu:fc09g08, anticorps MEL1, anticorps PFM13, anticorps 5730557K01Rik, anticorps C130091E20, anticorps csp1, anticorps mKIAA1675, anticorps mel1, anticorps PR/SET domain 16, anticorps PR domain containing 16, anticorps PRDM16, anticorps prdm16, anticorps Prdm16
    Sujet
    The reciprocal translocation t(1,3)(p36,q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Alias Symbols: KIAA1675, MEL1, PFM13
    Protein Interaction Partner: TFAP4, UBC, HDAC2, Ctbp2, SUMO1, SKI, SMAD3, SMAD2, INADL,
    Protein Size: 1275
    Poids moléculaire
    140 kDa
    ID gène
    63976
    NCBI Accession
    NM_022114, NP_071397
    UniProt
    Q9HAZ2
    Pathways
    Stem Cell Maintenance, Brown Fat Cell Differentiation
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