SHOX2 anticorps (Middle Region)

N° du produit ABIN2777840

Cet anticorps Lapin Polyclonal détecte spécifiquement SHOX2 dans WB. Il présente une réactivité envers Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Poisson zèbre (Danio rerio), Cheval et Lapin.

Aperçu rapide pour SHOX2 anticorps (Middle Region) (ABIN2777840)

Antigène: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Poisson zèbre (Danio rerio), Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHOX2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SHOX2 anticorps

Épitope: Middle Region

Séquence: SEARVQVWFQ NRRAKCRKQE NQLHKGVLIG AASQFEACRV APYVNVGALR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SHOX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SHOX2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 331 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SHOX2

Antigène: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Autre désignation: SHOX2

Sujet: SHOX2 is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.
Alias Symbols: OG12, OG12X, OGI2X, SHOT
Protein Interaction Partner: CDK4, ELAVL1, TRIM29, KDM5B,
Protein Size: 331

Poids moléculaire: 35 kDa

ID gène: 6474

NCBI Accession: NM_006884, NP_006875

UniProt: O60902

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development