BCL11B anticorps (Middle Region)

N° du produit ABIN2777845

L’anticorps Lapin Polyclonal anti-BCL11B a été validé pour WB et IHC. Il convient pour détecter BCL11B dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye et Cheval.

Aperçu rapide pour BCL11B anticorps (Middle Region) (ABIN2777845)

Antigène: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL11B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-BCL11B anticorps

Épitope: Middle Region

Séquence: QASKLKRHMK THMHKAGSLA GRSDDGLSAA SSPEPGTSEL AGEGLKAADG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against BCL11B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human BCL11B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 823 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur BCL11B

Antigène: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Autre désignation: BCL11B

Sujet: BCL11B is the tumor-suppressor protein involved in T-cell lymphomas. BCL11B may function on the P53-signaling pathway. BCL11B may be a key regulator of both differentiation and survival during thymocyte development. BCL11B repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element.This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.
Alias Symbols: CTIP-2, CTIP2, RIT1, hRIT1-alpha, ZNF856B
Protein Interaction Partner: HDAC6, HDAC2, HDAC1, NOTCH1, UBC, HDAC3, SUV39H1, tat, CBX5, NR2F1, SP1, MBD3, MTA2, MTA1, RBBP7, RBBP4, CHD4, NR2F2,
Protein Size: 823

Poids moléculaire: 88 kDa

ID gène: 64919

NCBI Accession: NM_022898, NP_075049