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SOX5 anticorps (C-Term)

SOX5 Reactivité: Humain, Rat, Souris, Lapin, Cobaye, Cheval, Boeuf (Vache), Chien WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2777862
  • Antigène Voir toutes SOX5 Anticorps
    SOX5 (SRY (Sex Determining Region Y)-Box 5 (SOX5))
    Épitope
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 20
    • 10
    • 9
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Rat, Souris, Lapin, Cobaye, Cheval, Boeuf (Vache), Chien
    Hôte
    • 14
    • 6
    Lapin
    Clonalité
    • 14
    • 6
    Polyclonal
    Conjugué
    • 20
    Cet anticorp SOX5 est non-conjugé
    Application
    • 16
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    PEPGMPVIQS TYGVKGEEPH IKEEIQAEDI NGEIYDEYDE EEDDPDVDYG
    Specificité
    Designed to recognize all five isoforms of human SOX5 (84, 82, 42, 71 and 83 kDa)
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against SOX5. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human SOX5
    Top Product
    Discover our top product SOX5 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 377 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Zhang, Liu, Li, Zhang, Li, Liu, Min, Shuang, Song, Zhang: "Transcriptional regulation of human sperm-associated antigen 16 gene by S-SOX5." dans: BMC molecular biology, Vol. 18, Issue 1, pp. 2, (2017) (PubMed).

    Naveau, Pinson, Gérard, Nguyen, Charlier, Thomé, Zoeller, Bourguignon, Parent: "Alteration of rat fetal cerebral cortex development after prenatal exposure to polychlorinated biphenyls." dans: PLoS ONE, Vol. 9, Issue 3, pp. e91903, (2014) (PubMed).

    Fernandes, Herlofsen, Karlsen, Küchler, Fløisand, Brinchmann: "Similar properties of chondrocytes from osteoarthritis joints and mesenchymal stem cells from healthy donors for tissue engineering of articular cartilage." dans: PLoS ONE, Vol. 8, Issue 5, pp. e62994, (2013) (PubMed).

    Boije, Harun-Or-Rashid, Lee, Imsland, Bruneau, Vieaud, Gourichon, Tixier-Boichard, Bedhom, Andersson, Hallböök: "Sonic Hedgehog-signalling patterns the developing chicken comb as revealed by exploration of the pea-comb mutation." dans: PLoS ONE, Vol. 7, Issue 12, pp. e50890, (2012) (PubMed).

    Yu, Deshmukh, Payton, Dunham, Scheithauer, Tihan, Prayson, Guha, Bridge, Ferner, Lindberg, Gutmann, Emnett, Salavaggione, Gutmann, Nagarajan, Watson, Perry: "Array-based comparative genomic hybridization identifies CDK4 and FOXM1 alterations as independent predictors of survival in malignant peripheral nerve sheath tumor." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 7, pp. 1924-34, (2011) (PubMed).

    Aza-Carmona, Shears, Yuste-Checa, Barca-Tierno, Hisado-Oliva, Belinchón, Benito-Sanz, Rodríguez, Argente, Campos-Barros, Scambler, Heath: "SHOX interacts with the chondrogenic transcription factors SOX5 and SOX6 to activate the aggrecan enhancer." dans: Human molecular genetics, Vol. 20, Issue 8, pp. 1547-59, (2011) (PubMed).

    Kiselak, Shen, Song, Gude, Wang, Brody, Strauss, Zhang: "Transcriptional regulation of an axonemal central apparatus gene, sperm-associated antigen 6, by a SRY-related high mobility group transcription factor, S-SOX5." dans: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30496-505, (2010) (PubMed).

    Pytel, Karrison, Can Gong, Tonsgard, Krausz, Montag: "Neoplasms with schwannian differentiation express transcription factors known to regulate normal schwann cell development." dans: International journal of surgical pathology, Vol. 18, Issue 6, pp. 449-57, (2010) (PubMed).

    Torii, Hashimoto-Torii, Levitt, Rakic: "Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling." dans: Nature, Vol. 461, Issue 7263, pp. 524-8, (2009) (PubMed).

    Wright, Boije, Meadows, Bedhom, Gourichon, Vieaud, Tixier-Boichard, Rubin, Imsland, Hallböök, Andersson: "Copy number variation in intron 1 of SOX5 causes the Pea-comb phenotype in chickens." dans: PLoS genetics, Vol. 5, Issue 6, pp. e1000512, (2009) (PubMed).

    Tchougounova, Jiang, Bråsäter, Lindberg, Kastemar, Asplund, Westermark, Uhrbom: "Sox5 can suppress platelet-derived growth factor B-induced glioma development in Ink4a-deficient mice through induction of acute cellular senescence." dans: Oncogene, Vol. 28, Issue 12, pp. 1537-48, (2009) (PubMed).

    Martelli, Isella, Mira, Fu, Cantarella, Medico: "Exploiting orthologue diversity for systematic detection of gain-of-function phenotypes." dans: BMC genomics, Vol. 9, pp. 254, (2008) (PubMed).

  • Antigène
    SOX5 (SRY (Sex Determining Region Y)-Box 5 (SOX5))
    Autre désignation
    SOX5 (SOX5 Produits)
    Synonymes
    anticorps L-SOX5, anticorps XSox-5, anticorps l-sox5, anticorps A730017D01Rik, anticorps AI528773, anticorps Sox5l1, anticorps xSox5, anticorps id:ibd5067, anticorps sb:eu456, anticorps si:dkey-215a8.1, anticorps SRY-box 5, anticorps SRY (sex determining region Y)-box 5, anticorps SRY box 5, anticorps SRY-box 5 S homeolog, anticorps SOX5, anticorps sox5, anticorps Sox5, anticorps sox5.S
    Sujet
    SOX5 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8.
    Alias Symbols: L-SOX5, MGC35153
    Protein Interaction Partner: SUMO1P1, MORN3, PRR20A, FAM46B, CBX8, ZNF581, ARID5A, KAT5, CDC23, TAF6, SOX5, LMO2, LMO1, KIFC3, CRX, AES, MED27, UQCRFS1, TTC1, RPS2, SMAD7, SMAD5, SMAD1, FTH1, CDK6, CDC25A, APP, SOX2, SOX6,
    Protein Size: 377
    Poids moléculaire
    42 kDa
    ID gène
    6660
    NCBI Accession
    NM_178010, NP_821078
    UniProt
    P35711
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