T-Box 6 anticorps (N-Term)
Aperçu rapide pour T-Box 6 anticorps (N-Term) (ABIN2777918)
Antigène
Voir toutes T-Box 6 (TBX6) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- TBX6 Antibody - N-terminal region
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Séquence
- AHPPLPLLPP AMGTEPAPSA PEALHSLPGV SLSLENRELW KEFSSVGTEM
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Homologie
- Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against TBX6. It was validated on Western Blot and immunohistochemistry.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human TBX6
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33405-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Smad6 inhibits the transcriptional activity of Tbx6 by mediating its degradation." dans: The Journal of biological chemistry, Vol. 284, Issue 35, pp. 23481-90, (2009) (PubMed).
: "Cardiac commitment of primate embryonic stem cells." dans: Nature protocols, Vol. 3, Issue 9, pp. 1381-7, (2008) (PubMed).
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- T-Box 6 (TBX6)
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Autre désignation
- TBX6
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Sujet
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Background Information: The TBX6 gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX6 is the human ortholog of mouse Tbx6. Knockout experiments in mice indicate that Tbx6 is important for specification of paraxial mesoderm structures.
Gene Name: T-box 6
Alternative Symbols: SCDO5
Protein Name: T-box transcription factor TBX6
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Poids moléculaire
- 47kDa
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ID gène
- 6911
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NCBI Accession
- NP_004599
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UniProt
- O95947
Antigène
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