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TBX3 anticorps (Middle Region)

L’anticorps Lapin Polyclonal anti-TBX3 a été validé pour WB. Il convient pour détecter TBX3 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye et Lapin. Il y a 2+ publications disponibles.
N° du produit ABIN2777925

Aperçu rapide pour TBX3 anticorps (Middle Region) (ABIN2777925)

Antigène

Voir toutes TBX3 Anticorps
TBX3 (T-Box 3 (TBX3))

Reactivité

  • 54
  • 19
  • 16
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin

Hôte

  • 54
  • 8
  • 1
Lapin

Clonalité

  • 53
  • 10
Polyclonal

Conjugué

  • 39
  • 9
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp TBX3 est non-conjugé

Application

  • 48
  • 26
  • 14
  • 10
  • 9
  • 6
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Séquence

    CRDKGSPAVK AHLFAAERPR DSGRLDKASP DSRHSPATIS SSTRGLGAEE

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    Attributs du produit

    This is a rabbit polyclonal antibody against TBX3. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Protein A purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the middle region of human TBX3
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 600 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bozyk, Popova, Bentley, Goldsmith, Linn, Weiss, Hershenson: "Mesenchymal stromal cells from neonatal tracheal aspirates demonstrate a pattern of lung-specific gene expression." dans: Stem cells and development, Vol. 20, Issue 11, pp. 1995-2007, (2011) (PubMed).

    Yano, Yamazaki, Adachi, Okawa, Fort, Uji, Tsukita, Tsukita: "Tara up-regulates E-cadherin transcription by binding to the Trio RhoGEF and inhibiting Rac signaling." dans: The Journal of cell biology, Vol. 193, Issue 2, pp. 319-32, (2011) (PubMed).

  • Antigène

    TBX3 (T-Box 3 (TBX3))

    Autre désignation

    TBX3

    Sujet

    TBX3 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms, however, the full length nature of one variant has not been determined.
    Alias Symbols: UMS, XHL, TBX3-ISO
    Protein Interaction Partner: CA8, AES, SOX2, Dlg4, ELAVL1, HDAC5, HDAC3, HDAC2, HDAC1, TOLLIP, TBX3,
    Protein Size: 600

    Poids moléculaire

    66 kDa

    ID gène

    6926

    Pathways

    Hormone Transport, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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