MLX anticorps (C-Term)

N° du produit ABIN2777933

L’anticorps Lapin Polyclonal anti-MLX a été validé pour WB et IHC. Il convient pour détecter MLX dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Chévre, Cheval et Lapin. Il y a 1 publication disponible.

Aperçu rapide pour MLX anticorps (C-Term) (ABIN2777933)

Antigène: MLX (MAX-Like Protein X (MLX))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Chévre, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLX est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-MLX anticorps

Épitope: C-Term

Séquence: LRKDVTALKI MKVNYEQIVK AHQDNPHEGE DQVSDQVKFN VFQGIMDSLF

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MLX. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human MLX

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 298 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-MLX (ABIN2777933)

Stoltzman, Peterson, Breen, Muoio, Billin, Ayer: "Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 19, pp. 6912-7, (2008) (PubMed).

Détails sur MLX

Antigène: MLX (MAX-Like Protein X (MLX))

Autre désignation: MLX

Sujet: MLX belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. MLX may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4.The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: MAD7, MXD7, TCFL4, bHLHd13
Protein Interaction Partner: ZBTB32, GABARAPL2, RBM39, AES, UBC, SAP30BP, ID3, APP, SUMO1, MLXIPL, MLXIP, MXD4, MNT, MAD1L1, MLX, MXD1,
Protein Size: 298

Poids moléculaire: 33 kDa

ID gène: 6945

NCBI Accession: NM_170607, NP_733752

UniProt: Q9UH92