Claudin 18 anticorps (Middle Region)

N° du produit ABIN2778037

Cet anticorps Lapin Polyclonal détecte spécifiquement Claudin 18 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Chien, Cheval, Lapin et Cobaye.

Aperçu rapide pour Claudin 18 anticorps (Middle Region) (ABIN2778037)

Antigène: Claudin 18 (CLDN18)

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 18 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Claudin 18 anticorps

Épitope: Middle Region

Fonction: CLDN18 Antibody - middle region

Séquence: YHASGHSVAY KPGGFKASTG FGSNTKNKKI YDGGARTEDE VQSYPSKHDY

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against CLDN18. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CLDN18

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33612-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Claudin 18

Antigène: Claudin 18 (CLDN18)

Autre désignation: CLDN18

Sujet:

Background Information: CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells (Niimi et al., 2001 [PubMed 11585919]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-282 AY358479.1 28-309 283-1864 AK098474.1 274-1855 1865-2307 BM785703.1 143-585 2308-2868 AK098474.1 2297-2857 2869-3359 AY102073.1 394-884

Gene Name: Claudin 18

Alternative Symbols: SFTA5, SFTPJ

Protein Name: Claudin-18

Poids moléculaire: 28kDa

ID gène: 51208

NCBI Accession: NP_057453

UniProt: P56856

Pathways: Cell-Cell Junction Organization, Hepatitis C