Cet anticorps anti-DKFZp686M216 est un anticorps Polyclonal produit chez le Lapin, détectant DKFZp686M216 dans WB. Convient pour Boeuf (Vache), Chien, Cobaye, Cheval, Humain, Souris, Lapin, Rat, Mouton et Poisson zèbre (Danio rerio).
This is a rabbit polyclonal antibody against DKFZp686M216. It was validated on Western Blot.
Purification
Affinity Purified
Immunogène
The immunogen is a synthetic peptide directed towards the N-terminal region of Human DKFZp686M216
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeat freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Antigène
DKFZp686M216
Sujet
This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. Alias Symbols: bHLHe1, DKFZp686M216 Protein Interaction Partner: TRIM42, CEP57L1, RFX6, MIPOL1, DYDC1, SSX2IP, DTX2, SYCE1, RIMBP3, ZNF341, LZTS2, USHBP1, CEP63, CCDC33, NPAS3, RINT1, NDE1, ADAMTSL4, MTUS2, IKZF3, RBCK1, SPAG5, TACC3, CALCOCO2, SORBS3, PDE4DIP, TRAF4, BZRAP1, TFIP11, SSBP3, DGCR6, NCOA3, TRIP6, TRAF2, Protein Size: 717