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DKFZp686M216 (N-Term) anticorps

Cet anticorps anti- est un anticorps Lapin Polyclonal détectant dans WB. Adapté pour Boeuf (Vache), Chien, Cobaye, Cheval, Humain, Souris, Lapin, Rat, Mouton et Poisson zèbre (Danio rerio).
N° du produit ABIN2778072

Aperçu rapide pour DKFZp686M216 (N-Term) anticorps (ABIN2778072)

Antigène

DKFZp686M216

Reactivité

Boeuf (Vache), Chien, Cobaye, Cheval, Humain, Souris, Lapin, Rat, Mouton, Poisson zèbre (Danio rerio)

Hôte

Lapin

Clonalité

Polyclonal

Application

Western Blotting (WB)
  • Épitope

    N-Term

    Séquence

    VTLPVAPMAA TGQVRMAGAM PARGGKRRSG MDFDDEDGEG PSKFSRENHS

    Specificité

    This antibody is specific to both isoforms of hARNT2.

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

    Attributs du produit

    This is a rabbit polyclonal antibody against DKFZp686M216. It was validated on Western Blot.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N-terminal region of Human DKFZp686M216
  • Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeat freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    DKFZp686M216

    Sujet

    This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.
    Alias Symbols: bHLHe1, DKFZp686M216
    Protein Interaction Partner: TRIM42, CEP57L1, RFX6, MIPOL1, DYDC1, SSX2IP, DTX2, SYCE1, RIMBP3, ZNF341, LZTS2, USHBP1, CEP63, CCDC33, NPAS3, RINT1, NDE1, ADAMTSL4, MTUS2, IKZF3, RBCK1, SPAG5, TACC3, CALCOCO2, SORBS3, PDE4DIP, TRAF4, BZRAP1, TFIP11, SSBP3, DGCR6, NCOA3, TRIP6, TRAF2,
    Protein Size: 717

    Poids moléculaire

    79 kDa

    ID gène

    9915

    UniProt

    Q9HBZ2
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