FOXP2 anticorps (N-Term)
Aperçu rapide pour FOXP2 anticorps (N-Term) (ABIN2778104)
Antigène
Voir toutes FOXP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- SGLKSPKSSD KQRPLQVPVS VAMMTPQVIT PQQMQQILQQ QVLSPQQLQA
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Specificité
- Isoform 4 and 5
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Homologie
- Dog: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%
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Attributs du produit
- This is a rabbit polyclonal antibody against FOXP2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human FOXP2
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 715 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FOXP2 (Forkhead Box P2 (FOXP2))
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Autre désignation
- FOXP2
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Sujet
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FOXP2 is an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Four alternative transcripts encoding three different isoforms have been identified.
Alias Symbols: SPCH1, CAGH44, TNRC10
Protein Interaction Partner: FAM124A, TSACC, RPIA, SP4, SDCBP, PIN1, CTBP2, CTBP1, CCNC, AES, MAPK3, HSP90AA1, GATAD2B, FOXP1, FOXP4, FOXP2,
Protein Size: 715 -
Poids moléculaire
- 80 kDa
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ID gène
- 93986
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NCBI Accession
- NM_014491, NP_055306
Antigène
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