FOXP2 anticorps (N-Term)

N° du produit ABIN2778105

Détail du produit anti-FOXP2 anticorps

Antigène: FOXP2 (Forkhead Box P2 (FOXP2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Porc, Chien, Lapin, Poisson zèbre (Danio rerio), Cheval, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: SGLKSPKSSD KQRPLQVPVS VAMMTPQVIT PQQMQQILQQ QVLSPQQLQA

Homologie: Dog: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%

Attributs du produit: This is a rabbit polyclonal antibody against FOXP2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FOXP2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 715 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FOXP2

Antigène: FOXP2 (Forkhead Box P2 (FOXP2))

Autre désignation: FOXP2 (FOXP2 Produits)

Synonymes: anticorps CAGH44, anticorps SPCH1, anticorps TNRC10, anticorps 2810043D05Rik, anticorps AI449000, anticorps CAG-16, anticorps D0Kist7, anticorps RGD1559697, anticorps FOXP2, anticorps spch1, anticorps cagh44, anticorps tnrc10, anticorps xlFoxP2, anticorps foxP2, anticorps foxP, anticorps Foxp2, anticorps foxP2b, anticorps foxp2a, anticorps forkhead box P2, anticorps lmw-gs, anticorps forkhead box transcription factor, anticorps forkhead box P2 L homeolog, anticorps FOXP2, anticorps Foxp2, anticorps foxp2, anticorps foxP2, anticorps foxp1c, anticorps foxp2.L

Sujet: FOXP2 is an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Four alternative transcripts encoding three different isoforms have been identified.This gene encodes an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Four alternative transcripts encoding three different isoforms have been identified.
Alias Symbols: CAGH44, DKFZp686H1726, SPCH1, TNRC10
Protein Interaction Partner: FAM124A, TSACC, RPIA, SP4, SDCBP, PIN1, CTBP2, CTBP1, CCNC, AES, MAPK3, HSP90AA1, GATAD2B, FOXP1, FOXP4, FOXP2,
Protein Size: 715

Poids moléculaire: 80 kDa

ID gène: 93986

NCBI Accession: NM_014491, NP_055306

UniProt: O15409