PARP11 anticorps (Middle Region)

N° du produit ABIN2778116

Cet anticorps anti-PARP11 Polyclonal Lapin (ABIN2778116) détecte spécifiquement PARP11 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye et Lapin.

Aperçu rapide pour PARP11 anticorps (Middle Region) (ABIN2778116)

Antigène: PARP11 (Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP11 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PARP11 anticorps

Épitope: Middle Region

Fonction: PARP11 Antibody - middle region

Séquence: IKHGNTFQIH GVSLQQRHLF RTYKSMFLAR VLIGDYINGD SKYMRPPSKD

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PARP11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PARP11

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33767-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PARP11

Antigène: PARP11 (Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))

Autre désignation: PARP11

Sujet:

Background Information: PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.

Gene Name: Poly (ADP-ribose) polymerase family, member 11

Alternative Symbols: ARTD11, MIB006, C12orf6

Protein Name: Poly [ADP-ribose] polymerase 11

Poids moléculaire: 39kDa

ID gène: 57097

NCBI Accession: NP_065100

UniProt: Q9NR21