Asialoglycoprotein Receptor 2 anticorps (N-Term)

N° du produit ABIN2778141

Cité dans 1 publication. Cet anticorps anti-Asialoglycoprotein Receptor 2 Polyclonal Lapin (ABIN2778141) détecte spécifiquement Asialoglycoprotein Receptor 2 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Porc, Rat et Saccharomyces cerevisiae.

Aperçu rapide pour Asialoglycoprotein Receptor 2 anticorps (N-Term) (ABIN2778141)

Antigène: Asialoglycoprotein Receptor 2 (ASGR2)

Reactivité: Humain, Porc, Rat, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Asialoglycoprotein Receptor 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Asialoglycoprotein Receptor 2 anticorps

Épitope: N-Term

Fonction: ASGR2 Antibody - N-terminal region

Séquence: LVVICVTGSQ SEGHRGAQLQ AELRSLKEAF SNFSSSTLTE VQAISTHGGS

Homologie: Human: 100%, Pig: 77%, Rat: 79%, Yeast: 77%

Attributs du produit: This is a rabbit polyclonal antibody against ASGR2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ASGR2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8095047

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Asialoglycoprotein Receptor 2 (ABIN2778141)

Chang, Lai, Chien, Liang, Adak, Chuang, Chen, Lin: "Synthesis and evaluation of a photoactive probe with a multivalent carbohydrate for capturing carbohydrate-lectin interactions." dans: Bioconjugate chemistry, Vol. 24, Issue 11, pp. 1895-906, (2013) (PubMed).

Détails sur Asialoglycoprotein Receptor 2

Antigène: Asialoglycoprotein Receptor 2 (ASGR2)

Autre désignation: ASGR2

Sujet:

Background Information: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: asialoglycoprotein receptor 2

Alternative Symbols: HL-2, HBXBP, ASGPR2, ASGP-R2, CLEC4H2

Protein Name: Asialoglycoprotein receptor 2

Poids moléculaire: 35kDa

ID gène: 433

NCBI Accession: NP_001172

UniProt: P07307

Pathways: Thyroid Hormone Synthesis