PLP1 anticorps (N-Term)

N° du produit ABIN2778151

L’anticorps anti-PLP1 Polyclonal produit chez le Lapin a été validé pour WB et IHC. Il convient pour la détection de PLP1 dans des échantillons provenant de Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio). }

Aperçu rapide pour PLP1 anticorps (N-Term) (ABIN2778151)

Antigène: PLP1 (Proteolipid Protein 1 (PLP1))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PLP1 anticorps

Épitope: N-Term

Séquence: GHEALTGTEK LIETYFSKNY QDYEYLINVI HAFQYVIYGT ASFFFLYGAL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 75%

Attributs du produit: This is a rabbit polyclonal antibody against PLP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PLP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 277 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PLP1

Antigène: PLP1 (Proteolipid Protein 1 (PLP1))

Autre désignation: PLP1

Sujet: PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.
Alias Symbols: MMPL, PLP, PLP/DM20, PMD, SPG2, HLD1
Protein Interaction Partner: PTPRN, CLN8, Htt, ITGAV, ITGA5, MAG, MBP, CANX, CALR,
Protein Size: 277

Poids moléculaire: 30 kDa

ID gène: 5354

NCBI Accession: NM_000533, NP_000524

UniProt: P60201