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PLP1 anticorps (Middle Region)

PLP1 Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2778152
  • Antigène Voir toutes PLP1 Anticorps
    PLP1 (Proteolipid Protein 1 (PLP1))
    Épitope
    • 16
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 32
    • 24
    • 11
    • 9
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin
    Hôte
    • 36
    • 11
    • 3
    Lapin
    Clonalité
    • 40
    • 10
    Polyclonal
    Conjugué
    • 25
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PLP1 est non-conjugé
    Application
    • 41
    • 20
    • 16
    • 13
    • 13
    • 12
    • 9
    • 7
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    IYGTASFFFL YGALLLAEGF YTTGAVRQIF GDYKTTICGK GLSATVTGGQ
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against PLP1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human PLP1
    Top Product
    Discover our top product PLP1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 277 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    PLP1 (Proteolipid Protein 1 (PLP1))
    Autre désignation
    PLP1 (PLP1 Produits)
    Synonymes
    anticorps GPM6C, anticorps HLD1, anticorps MMPL, anticorps PLP, anticorps PLP/DM20, anticorps PMD, anticorps SPG2, anticorps Plp, anticorps PLP1, anticorps plp1, anticorps DKFZp459O081, anticorps DKFZp459O113, anticorps DM20, anticorps jimpy, anticorps jp, anticorps msd, anticorps rsh, anticorps plp, anticorps hld1, anticorps mmpl, anticorps plp1a, anticorps pmd, anticorps spg2, anticorps DMalpha2c, anticorps wu:fc27f01, anticorps wu:fj36d03, anticorps wu:fj42d08, anticorps zgc:110499, anticorps PLP-B, anticorps plp1-a, anticorps plp1-b, anticorps plp1b, anticorps proteolipid protein 1, anticorps proteolipid protein (myelin) 1, anticorps myelin proteolipid protein, anticorps proteolipid protein 1 L homeolog, anticorps proteolipid protein 1a, anticorps proteolipid protein 1 S homeolog, anticorps PLP1, anticorps Plp1, anticorps plp1, anticorps Tsp_11640, anticorps plp, anticorps plp1.L, anticorps plp1a, anticorps plp1.S
    Sujet
    PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2.This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.
    Alias Symbols: MMPL, PLP, PLP/DM20, PMD, SPG2, HLD1
    Protein Interaction Partner: PTPRN, CLN8, Htt, ITGAV, ITGA5, MAG, MBP, CANX, CALR,
    Protein Size: 277
    Poids moléculaire
    30 kDa
    ID gène
    5354
    NCBI Accession
    NM_000533, NP_000524
    UniProt
    P60201
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