TRP63 anticorps (Middle Region)

N° du produit ABIN2778222

Cet anticorps anti-TRP63 Polyclonal Lapin (ABIN2778222) détecte spécifiquement TRP63 dans WB. L’anticorps est réactif avec des échantillons de Humain, Boeuf (Vache), Chien, Cobaye, Cheval, Souris, Lapin, Rat et Poisson zèbre (Danio rerio).

Aperçu rapide pour TRP63 anticorps (Middle Region) (ABIN2778222)

Antigène: TRP63 (Transformation Related Protein 63 (TRP63))

Reactivité: Humain, Boeuf (Vache), Chien, Cobaye, Cheval, Souris, Lapin, Rat, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRP63 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TRP63 anticorps

Épitope: Middle Region

Fonction: Trp63 Antibody - middle region

Séquence: VTLETRDGQV LGRRCFEARI CACPGRDRKA DEDSIRKQQV SDSAKNGDGT

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against Trp63. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33997-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur TRP63

Antigène: TRP63 (Transformation Related Protein 63 (TRP63))

Autre désignation: Trp63

Sujet:

Background Information: This gene encodes tumor protein p63, a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include tumor proteins p53, p63, and p73, which have high sequence similarity to one another. This similarity allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways, including direct and indirect protein interactions. This results in mutual regulation of target gene promoters. Tumor protein p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium.

Gene Name: Transformation related protein 63

Alternative Symbols: p6, p7, Ket, P63, TAp, P73l, Tp63, Trp5, delta, p51/p, P51/P63, AI462811, Trp53rp1

Protein Name: Tumor protein 63

Poids moléculaire: 50kDa

ID gène: 22061

NCBI Accession: NP_001108450

UniProt: Q9H3D4