TRP63 anticorps (Middle Region)

N° du produit ABIN2778222

Détail du produit anti-TRP63 anticorps

Antigène: TRP63 (Transformation Related Protein 63 (TRP63))

Épitope: Middle Region

Reactivité: Humain, Souris, Lapin, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRP63 est non-conjugé

Application: Western Blotting (WB)

Séquence: VTLETRDGQV LGRRCFEARI CACPGRDRKA DEDSIRKQQV SDSAKNGDGT

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against Trp63. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 461 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TRP63

Antigène: TRP63 (Transformation Related Protein 63 (TRP63))

Autre désignation: Trp63 (TRP63 Produits)

Synonymes: anticorps AI462811, anticorps Ket, anticorps P51/P63, anticorps P63, anticorps P73l, anticorps Tp63, anticorps Trp53rp1, anticorps transformation related protein 63, anticorps Trp63

Sujet: This gene encodes tumor protein p63, a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include tumor proteins p53, p63, and p73, which have high sequence similarity to one another. This similarity allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways, including direct and indirect protein interactions. This results in mutual regulation of target gene promoters. Tumor protein p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium.
Alias Symbols: AI462811, Ket, MGC115972, P51/P63, P63, P73l, Tp63, Trp53rp1
Protein Interaction Partner: Trp53, Dlx6, Dlx5, Abbp1, Trp73, Perp,
Protein Size: 461

Poids moléculaire: 50 kDa

ID gène: 22061

NCBI Accession: NM_001114978, NP_001108450

UniProt: Q9H3D4