Tryptophan Hydroxylase 2 anticorps (N-Term)

N° du produit ABIN2778285

Cet anticorps Lapin Polyclonal détecte spécifiquement Tryptophan Hydroxylase 2 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye et Porc.Il a été cité dans 1 publication.

Aperçu rapide pour Tryptophan Hydroxylase 2 anticorps (N-Term) (ABIN2778285)

Antigène: Tryptophan Hydroxylase 2 (TPH2)

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tryptophan Hydroxylase 2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Tryptophan Hydroxylase 2 anticorps

Épitope: N-Term

Fonction: TPH2 Antibody - N-terminal region

Séquence: REAATESGKT AVVFSLKNEV GGLVKALRLF QEKRVNMVHI ESRKSRRRSS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 83%, Horse: 85%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against TPH2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TPH2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34141-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Tryptophan Hydroxylase 2 (ABIN2778285)

Walther, Peter, Bashammakh, Hörtnagl, Voits, Fink, Bader: "Synthesis of serotonin by a second tryptophan hydroxylase isoform." dans: Science (New York, N.Y.), Vol. 299, Issue 5603, pp. 76, (2003) (PubMed).

Détails sur Tryptophan Hydroxylase 2

Antigène: Tryptophan Hydroxylase 2 (TPH2)

Autre désignation: TPH2

Sujet:

Background Information: Tryptophan hydroxylase (TPH, EC 1.14.16.4) is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including the maintenance of vascular tone and gut motility.

Gene Name: Tryptophan hydroxylase 2

Alternative Symbols: NTPH, ADHD7

Protein Name: Tryptophan 5-hydroxylase 2

Poids moléculaire: 56kDa

ID gène: 121278

NCBI Accession: NP_775489

UniProt: Q8IWU9