Tryptophan Hydroxylase 2 anticorps (N-Term)

N° du produit ABIN2778285

Détail du produit anti-Tryptophan Hydroxylase 2 anticorps

Antigène: Tryptophan Hydroxylase 2 (TPH2)

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Cobaye, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tryptophan Hydroxylase 2 est non-conjugé

Application: Western Blotting (WB)

Séquence: REAATESGKT AVVFSLKNEV GGLVKALRLF QEKRVNMVHI ESRKSRRRSS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 83%, Horse: 85%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against TPH2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TPH2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 490 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Tryptophan Hydroxylase 2 (ABIN2778285)

Walther, Peter, Bashammakh, Hörtnagl, Voits, Fink, Bader: "Synthesis of serotonin by a second tryptophan hydroxylase isoform." dans: Science (New York, N.Y.), Vol. 299, Issue 5603, pp. 76, (2003) (PubMed).

Détails sur Tryptophan Hydroxylase 2

Antigène: Tryptophan Hydroxylase 2 (TPH2)

Autre désignation: TPH2 (TPH2 Produits)

Synonymes: anticorps ADHD7, anticorps NTPH, anticorps Ntph, anticorps tphR, anticorps wu:fq15a04, anticorps AU043594, anticorps tryptophan hydroxylase 2, anticorps tryptophan hydroxylase 2 (tryptophan 5-monooxygenase), anticorps TPH2, anticorps Tph2, anticorps tph2

Sujet: Tryptophan hydroxylase (TPH, EC 1.14.16.4) is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including the maintenance of vascular tone and gut motility.
Alias Symbols: NTPH, ADHD7
Protein Interaction Partner: UBC,
Protein Size: 490

Poids moléculaire: 56 kDa

ID gène: 121278

NCBI Accession: NM_173353, NP_775489

UniProt: Q8IWU9