Atrophin 1 anticorps (N-Term)

N° du produit ABIN501239

L’anticorps anti-Atrophin 1 Polyclonal Lapin est utilisé pour la détection de Atrophin 1 dans des échantillons de Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval et Porc. Il a été validé pour WB.

Aperçu rapide pour Atrophin 1 anticorps (N-Term) (ABIN501239)

Antigène: Atrophin 1 (ATN1)

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Atrophin 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Atrophin 1 anticorps

Épitope: N-Term

Fonction: ATN1 Antibody - N-terminal region

Séquence: VSTSSSDGKA EKSRQTAKKA RVEEASTPKV NKQGRSEEIS ESESEETNAP

Homologie: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ATN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ATN1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34153-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Atrophin 1

Antigène: Atrophin 1 (ATN1)

Autre désignation: ATN1

Sujet:

Background Information: Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within ATN1. The protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.

Gene Name: Atrophin 1

Alternative Symbols: B37, HRS, NOD, DRPLA, CHEDDA, D12S755E

Protein Name: Atrophin-1

Poids moléculaire: 125kDa

ID gène: 1822

NCBI Accession: NP_001931

UniProt: P54259