PAX8 anticorps (C-Term)

N° du produit ABIN2778308

Cet anticorps Lapin Polyclonal détecte spécifiquement PAX8 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Cobaye et Porc.

Aperçu rapide pour PAX8 anticorps (C-Term) (ABIN2778308)

Antigène: PAX8 (Paired Box 8 (PAX8))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAX8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PAX8 anticorps

Épitope: C-Term

Séquence: TPSNTPLGRN LSTHQTYPVV ADPHSPFAIK QETPEVSSSS STPSSLSSSA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against PAX8. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PAX8

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PAX8

Antigène: PAX8 (Paired Box 8 (PAX8))

Autre désignation: PAX8

Sujet: PAX8 is a member of the paired box (PAX) family of transcription factors. Members of this family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in its gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.
Alias Symbols: -
Protein Interaction Partner: SERINC1, ANXA7, PKM, CXCL9, CHUK, POU2AF1, WBP2, SMAD3, EP300, NKX2-1, ID2,
Protein Size: 450

Poids moléculaire: 48 kDa

ID gène: 7849

NCBI Accession: NM_013992, NP_054698

UniProt: Q06710

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation