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MED6 anticorps (Middle Region)

MED6 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye WB, ChIP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2778335
  • Antigène Voir toutes MED6 Anticorps
    MED6 (Mediator Complex Subunit 6 (MED6))
    Épitope
    • 12
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 55
    • 10
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye
    Hôte
    • 50
    • 5
    Lapin
    Clonalité
    • 52
    • 3
    Polyclonal
    Conjugué
    • 28
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MED6 est non-conjugé
    Application
    • 48
    • 31
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
    Séquence
    ALLLDLRQKF PPKFVQLKPG EKPVPVDQTK KEAEPIPETV KPEEKETTKN
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against MED6. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human MED6
    Top Product
    Discover our top product MED6 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 246 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    MED6 (Mediator Complex Subunit 6 (MED6))
    Autre désignation
    MED6 (MED6 Produits)
    Synonymes
    anticorps NY-REN-28, anticorps wu:fa14c11, anticorps zgc:86933, anticorps 1500012F11Rik, anticorps AU019660, anticorps AV213303, anticorps RNA polymerase transcriptional regulation mediator-like protein, anticorps mediator complex subunit 6, anticorps hypothetical protein, anticorps MED6, anticorps Med6, anticorps med6, anticorps CAALFM_C306170CA
    Sujet
    MED6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. And mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    Alias Symbols: NY-REN-28
    Protein Interaction Partner: TARDBP, UBC, CDK19, CDK8, MED10, MED23, CCNC, MED19, MED26, FBXW7, MED11, MED28, MED29, MED4, MED12, MED7, MED21, MED1, SMARCA4, BCL6, SUZ12, CUL1, SKP1, CTDP1, MED25, SREBF1, MED15, VDR, OBFC1, MED18, ZC3H13, TADA2A, RARA, PARP1, SMAD3, SMAD2, SMAD1, MED
    Protein Size: 246
    Poids moléculaire
    28 kDa
    ID gène
    10001
    NCBI Accession
    NM_005466, NP_005457
    UniProt
    O75586
    Pathways
    Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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