MED6 anticorps (Middle Region)

N° du produit ABIN2778336

Cet anticorps anti-MED6 est un anticorps Lapin Polyclonal détectant MED6 dans WB et ChIP. Adapté pour Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye et Porc.

Aperçu rapide pour MED6 anticorps (Middle Region) (ABIN2778336)

Antigène: MED6 (Mediator Complex Subunit 6 (MED6))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED6 est non-conjugé

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Détail du produit anti-MED6 anticorps

Épitope: Middle Region

Séquence: LLLDLRQKFP PKFVQLKPGE KPVPVDQTKK EAEPIPETVK PEEKETTKNV

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MED6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MED6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 246 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MED6

Antigène: MED6 (Mediator Complex Subunit 6 (MED6))

Autre désignation: MED6

Sujet: MED6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. And mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Alias Symbols: NY-REN-28
Protein Interaction Partner: TARDBP, UBC, CDK19, CDK8, MED10, MED23, CCNC, MED19, MED26, FBXW7, MED11, MED28, MED29, MED4, MED12, MED7, MED21, MED1, SMARCA4, BCL6, SUZ12, CUL1, SKP1, CTDP1, MED25, SREBF1, MED15, VDR, OBFC1, MED18, ZC3H13, TADA2A, RARA, PARP1, SMAD3, SMAD2, SMAD1, MED
Protein Size: 246

Poids moléculaire: 28 kDa

ID gène: 10001

NCBI Accession: NM_005466, NP_005457

UniProt: O75586

Pathways: Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha