AFF3 anticorps (Middle Region)

N° du produit ABIN2778345

Cet anticorps Lapin Polyclonal détecte spécifiquement AFF3 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Porc, Lapin, Rat et Chien.Il a été cité dans 1 publication.

Aperçu rapide pour AFF3 anticorps (Middle Region) (ABIN2778345)

Antigène: AFF3 (AF4/FMR2 Family, Member 3 (AFF3))

Reactivité: Humain, Souris, Porc, Lapin, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AFF3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-AFF3 anticorps

Épitope: Middle Region

Fonction: AFF3 Antibody - middle region

Séquence: APATKDSESA PPSHTSDTPA EKALPKSKRK RKCDNEDDYR EIKKSQGEKD

Homologie: Dog: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 77%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against AFF3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human AFF3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34237-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-AFF3 (ABIN2778345)

To, Faseruk, Gokgoz, Pinnaduwage, Done, Andrulis: "LAF-4 is aberrantly expressed in human breast cancer." dans: International journal of cancer. Journal international du cancer, Vol. 115, Issue 4, pp. 568-74, (2005) (PubMed).

Détails sur AFF3

Antigène: AFF3 (AF4/FMR2 Family, Member 3 (AFF3))

Autre désignation: AFF3

Sujet:

Background Information: AFF3 is a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL.This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Gene Name: AF4/FMR2 family, member 3

Alternative Symbols: LAF4, MLLT2-like

Protein Name: AF4/FMR2 family member 3

Poids moléculaire: 134 kDa

ID gène: 3899

NCBI Accession: NP_002276

UniProt: P51826