IKZF3 anticorps (Middle Region)
Aperçu rapide pour IKZF3 anticorps (Middle Region) (ABIN2778395)
Antigène
Voir toutes IKZF3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- YACQRRDALT GHLRTHSVEK PYKCEFCGRS YKQRSSLEEH KERCRTFLQS
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Homologie
- Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%, Yeast: 83%
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Attributs du produit
- This is a rabbit polyclonal antibody against IKZF3. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human IKZF3
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
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Autre désignation
- IKZF3
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Sujet
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IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
Protein Interaction Partner: STAMBPL1, EXOSC5, LGALS14, CABP5, PCID2, RCOR3, TBC1D22B, FANCL, MAGOHB, C1orf109, OAZ3, SPG21, CHCHD2, OSGIN1, POLM, PPP1R16B, ABLIM3, IKZF3, NEK6, FARS2, MRPL28, KAT5, BCAS2, AKAP9, FAM115A, EMC2, POLR1C, STX11, STK16, RAD51D, PSMA1, PRKAB2, PRKAA1, PIN
Protein Size: 263 -
Poids moléculaire
- 28 kDa
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ID gène
- 22806
Antigène
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