MLX anticorps (C-Term)

N° du produit ABIN2778546

L’anticorps Lapin Polyclonal anti-MLX a été validé pour WB et IHC. Il convient pour détecter MLX dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Chévre, Cheval, Lapin et Poisson zèbre (Danio rerio). Il y a 1 publication disponible.

Aperçu rapide pour MLX anticorps (C-Term) (ABIN2778546)

Antigène: MLX (MAX-Like Protein X (MLX))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Chévre, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLX est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-MLX anticorps

Épitope: C-Term

Séquence: LRKDVTALKI MKVNYEQIVK AHQDNPHEGE DQVSDQVKFN VFQGIMDSLF

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against MLX. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human MLX

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 298 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-MLX (ABIN2778546)

Stoltzman, Peterson, Breen, Muoio, Billin, Ayer: "Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 19, pp. 6912-7, (2008) (PubMed).

Détails sur MLX

Antigène: MLX (MAX-Like Protein X (MLX))

Autre désignation: MLX

Sujet: MLX belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. MLX may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4.The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: MAD7, MXD7, TCFL4, bHLHd13
Protein Interaction Partner: ZBTB32, GABARAPL2, RBM39, AES, UBC, SAP30BP, ID3, APP, SUMO1, MLXIPL, MLXIP, MXD4, MNT, MAD1L1, MLX, MXD1,
Protein Size: 298

Poids moléculaire: 33 kDa

ID gène: 6945

NCBI Accession: NM_170607, NP_733752

UniProt: Q9UH92