RNF34 anticorps (Middle Region)

N° du produit ABIN2778633

Cet anticorps Lapin Polyclonal détecte spécifiquement RNF34 dans WB. Il présente une réactivité envers Humain, Rat, Boeuf (Vache), Chien, Lapin, Cheval et Cobaye.

Aperçu rapide pour RNF34 anticorps (Middle Region) (ABIN2778633)

Antigène: RNF34 (Ring Finger Protein 34 (RNF34))

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Lapin, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF34 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RNF34 anticorps

Épitope: Middle Region

Séquence: LVDLVLCHHG LGSEDDMDTS SLNSSRSQTS SFFTRSFFSN YTAPSATMSS

Homologie: Cow: 87%, Dog: 93%, Guinea Pig: 80%, Horse: 93%, Human: 100%, Rabbit: 80%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against RNF34. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RNF34

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 372 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RNF34

Antigène: RNF34 (Ring Finger Protein 34 (RNF34))

Autre désignation: RNF34

Sujet: RNF34 contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis.The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: FLJ21786, RFI, RIF, RIFF, hRFI, CARP1, CARP-1
Protein Interaction Partner: APPBP2, NOD1, APP, PRKACB, PHF7, TRIM23, UBE2D2, CASP10, CASP8, FZR1, ANAPC2, CDC20, SH3KBP1, PPARGC1A, TP53, UBE2F, UBE2H, DNAJA3,
Protein Size: 372

Poids moléculaire: 42 kDa

ID gène: 80196

NCBI Accession: NM_025126, NP_079402

UniProt: Q969K3