RNF34 anticorps (Middle Region)
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- Antigène Voir toutes RNF34 Anticorps
- RNF34 (Ring Finger Protein 34 (RNF34))
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Épitope
- Middle Region
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Reactivité
- Humain, Rat, Boeuf (Vache), Chien, Lapin, Cheval, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RNF34 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LVDLVLCHHG LGSEDDMDTS SLNSSRSQTS SFFTRSFFSN YTAPSATMSS
- Homologie
- Cow: 87%, Dog: 93%, Guinea Pig: 80%, Horse: 93%, Human: 100%, Rabbit: 80%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against RNF34. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human RNF34
- Top Product
- Discover our top product RNF34 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 372 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- RNF34 (Ring Finger Protein 34 (RNF34))
- Autre désignation
- RNF34 (RNF34 Produits)
- Synonymes
- anticorps CARP-1, anticorps CARP1, anticorps RFI, anticorps RIF, anticorps RIFF, anticorps hRFI, anticorps rnf34, anticorps AW061037, anticorps AW536122, anticorps BC004042, anticorps C88279, anticorps Momo, anticorps fi35g06, anticorps wu:fi35g06, anticorps zgc:114043, anticorps zgc:171755, anticorps ring finger protein 34, anticorps E3 ubiquitin-protein ligase RNF34, anticorps ring finger protein 34a, anticorps ring finger protein 34b, anticorps Residual feed intake, anticorps RNF34, anticorps rnf34, anticorps Rnf34, anticorps rnf34a, anticorps rnf34b, anticorps RFI
- Sujet
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RNF34 contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis.The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: FLJ21786, RFI, RIF, RIFF, hRFI, CARP1, CARP-1
Protein Interaction Partner: APPBP2, NOD1, APP, PRKACB, PHF7, TRIM23, UBE2D2, CASP10, CASP8, FZR1, ANAPC2, CDC20, SH3KBP1, PPARGC1A, TP53, UBE2F, UBE2H, DNAJA3,
Protein Size: 372 - Poids moléculaire
- 42 kDa
- ID gène
- 80196
- NCBI Accession
- NM_025126, NP_079402
- UniProt
- Q969K3
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