PRMT7 anticorps (C-Term)

N° du produit ABIN2778660

L’anticorps Lapin Polyclonal anti-PRMT7 a été validé pour WB. Il convient pour détecter PRMT7 dans des échantillons de Humain, Souris, Rat, Chien, Cheval et Cobaye.

Aperçu rapide pour PRMT7 anticorps (C-Term) (ABIN2778660)

Antigène: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRMT7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PRMT7 anticorps

Épitope: C-Term

Séquence: GEINDQDRTD HYAQALRTVL LPGSVCLCVS DGSLLSMLAH HLGAEQVFTV

Homologie: Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against Prmt7. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 692 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PRMT7

Antigène: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Autre désignation: Prmt7

Sujet: Prmt7 is a arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. It specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. It plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. It may also play a role in embryonic stem cell (ESC) pluripotency. It also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro, the relevance of such results is however unclear in vivo.
Alias Symbols: 4933402B05Rik, BC006705, MGC7929
Protein Interaction Partner: Ctcfl,
Protein Size: 692

Poids moléculaire: 78 kDa

ID gène: 214572

NCBI Accession: NM_145404, NP_663379

UniProt: Q922X9

Pathways: Ribonucleoprotein Complex Subunit Organization