PRMT7 anticorps (C-Term)

N° du produit ABIN2778660

L’anticorps anti-PRMT7 Polyclonal Lapin est utilisé pour la détection de PRMT7 dans des échantillons de Humain, Souris, Rat, Chien, Cheval et Cobaye. Il a été validé pour WB.

Aperçu rapide pour PRMT7 anticorps (C-Term) (ABIN2778660)

Antigène: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRMT7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PRMT7 anticorps

Épitope: C-Term

Fonction: Prmt7 Antibody - C-terminal region

Séquence: GEINDQDRTD HYAQALRTVL LPGSVCLCVS DGSLLSMLAH HLGAEQVFTV

Homologie: Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against Prmt7. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40192-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PRMT7

Antigène: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Autre désignation: Prmt7

Sujet:

Background Information: Prmt7 is a arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. It specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. It plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. It may also play a role in embryonic stem cell (ESC) pluripotency. It also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro, the relevance of such results is however unclear in vivo.

Gene Name: Protein arginine N-methyltransferase 7

Alternative Symbols: BC006705, 4933402B05Rik

Protein Name: Protein arginine N-methyltransferase 7

Poids moléculaire: 78kDa

ID gène: 214572

NCBI Accession: NP_663379

UniProt: Q922X9

Pathways: Ribonucleoprotein Complex Subunit Organization