HNRNPL anticorps (N-Term)

N° du produit ABIN2778695

Cet anticorps anti-HNRNPL est un anticorps Lapin Polyclonal détectant HNRNPL dans WB et IHC. Adapté pour Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour HNRNPL anticorps (N-Term) (ABIN2778695)

Antigène: HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNRNPL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-HNRNPL anticorps

Épitope: N-Term

Séquence: DTWDYTNPNL SGQGDPGSNP NKRQRQPPLL GDHPAEYGGP HGGYHSHYHD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%

Attributs du produit: This is a rabbit polyclonal antibody against HNRPL. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPL

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 589 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HNRNPL

Antigène: HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

Autre désignation: HNRPL

Sujet: Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: P/OKcl.14, hnRNP-L, HNRPL
Protein Interaction Partner: TP53, FUS, TRIM68, SUMO2, SUMO3, IVNS1ABP, UBC, MDM2, RPA3, RPA2, RPA1, ILF3, HNRNPA2B1, EED, VHL, VEGFA, RNF2, NEDD4, ITCH, FBXO6, HMGA1, vif, TP63, UBL4A, WHSC1, VCAM1, ITGA4, IL7R, IFIT3, IFIT2, FN1, DAB2, CSNK2A1, EIF4A3, MAGOH, HNRNPA3, NPLOC4, LSM14
Protein Size: 589

Poids moléculaire: 65 kDa

ID gène: 3191

NCBI Accession: NM_001533, NP_001524

UniProt: P14866