CARS anticorps (Middle Region)

N° du produit ABIN2778727

Cet anticorps anti-CARS Polyclonal Lapin (ABIN2778727) détecte spécifiquement CARS dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Lapin, Chien, Cheval, Boeuf (Vache), Poisson zèbre (Danio rerio) et Cobaye.

Aperçu rapide pour CARS anticorps (Middle Region) (ABIN2778727)

Antigène: CARS (Cysteinyl-tRNA Synthetase (CARS))

Reactivité: Humain, Souris, Rat, Lapin, Chien, Cheval, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CARS est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CARS anticorps

Épitope: Middle Region

Fonction: CARS Antibody - middle region

Séquence: QEQEAAKLAK MKIPPSEMFL SETDKYSKFD ENGLPTHDME GKELSKGQAK

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against CARS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CARS

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40294-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CARS

Antigène: CARS (Cysteinyl-tRNA Synthetase (CARS))

Autre désignation: CARS

Sujet:

Background Information: CARS is a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. CARS gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Gene Name: Cysteinyl-tRNA synthetase

Alternative Symbols: CARS, MDBH, CYSRS, MCDDBH, MGC:11246

Protein Name: Cysteine--tRNA ligase, cytoplasmic

Poids moléculaire: 85 kDa

ID gène: 833

NCBI Accession: NP_001014437

UniProt: Q5HYE4