RED1 anticorps (N-Term)

N° du produit ABIN2778757

Cet anticorps anti-RED1 est un anticorps Lapin Polyclonal détectant RED1 dans WB. Adapté pour Humain, Rat, Souris, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cheval, Cobaye et Lapin. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour RED1 anticorps (N-Term) (ABIN2778757)

Antigène: RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

Reactivité: Humain, Rat, Souris, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cheval, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RED1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RED1 anticorps

Épitope: N-Term

Séquence: QLSNGGGGGP GRKRPLEEGS NGHSKYRLKK RRKTPGPVLP KNALMQLNEI

Homologie: Cow: 83%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against ADARB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ADARB1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 701 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-RED1 (ABIN2778757)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." dans: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Détails sur RED1

Antigène: RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

Autre désignation: ADARB1

Sujet: ADARB1 is an enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site.This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.
Alias Symbols: RED1, ADAR2, DRABA2, DRADA2
Protein Interaction Partner: EBNA1BP2, IFRD2, CCDC124, NIFK, C7orf50, C1orf35, STRBP, BRIX1, SDAD1, ZFR, NOP16, MRTO4, RRS1, BMI1, APP, UBC, PPP2CB, WWP2, PIN1,
Protein Size: 701

Poids moléculaire: 77 kDa

ID gène: 104

NCBI Accession: NM_001112, NP_001103

UniProt: Q4AE79