RED1 anticorps (N-Term)

N° du produit ABIN2778757

Détail du produit anti-RED1 anticorps

Antigène: RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cheval, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RED1 est non-conjugé

Application: Western Blotting (WB)

Séquence: QLSNGGGGGP GRKRPLEEGS NGHSKYRLKK RRKTPGPVLP KNALMQLNEI

Homologie: Cow: 83%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against ADARB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ADARB1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 701 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-RED1 (ABIN2778757)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." dans: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Détails sur RED1

Antigène: RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

Autre désignation: ADARB1 (ADARB1 Produits)

Synonymes: anticorps ADARB1, anticorps RED1, anticorps ADAR2, anticorps DRABA2, anticorps DRADA2, anticorps 1700057H01Rik, anticorps AW124433, anticorps AW558573, anticorps Adar2, anticorps BB220382, anticorps D10Bwg0447e, anticorps Red1, anticorps adar2, anticorps adarb1, anticorps red1, anticorps adenosine deaminase, RNA specific B1, anticorps adenosine deaminase, RNA-specific, B1, anticorps adenosine deaminase, RNA-specific, B1 L homeolog, anticorps adenosine deaminase, RNA-specific, B1a, anticorps ADARB1, anticorps adarb1, anticorps adarb1.L, anticorps Adarb1, anticorps adarb1a

Sujet: ADARB1 is an enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site.This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.
Alias Symbols: RED1, ADAR2, DRABA2, DRADA2
Protein Interaction Partner: EBNA1BP2, IFRD2, CCDC124, NIFK, C7orf50, C1orf35, STRBP, BRIX1, SDAD1, ZFR, NOP16, MRTO4, RRS1, BMI1, APP, UBC, PPP2CB, WWP2, PIN1,
Protein Size: 701

Poids moléculaire: 77 kDa

ID gène: 104

NCBI Accession: NM_001112, NP_001103

UniProt: Q4AE79