RED1 anticorps (Adenosine Deaminase, RNA-Specific, B1) (N-Term)

Details for Product anti-ADARB1 Antibody No. ABIN2778757
Antigène
  • ADARB1
  • RED1
  • ADAR2
  • DRABA2
  • DRADA2
  • 1700057H01Rik
  • AW124433
  • AW558573
  • Adar2
  • BB220382
  • D10Bwg0447e
  • Red1
  • adar2
  • adarb1
  • red1
  • adenosine deaminase, RNA specific B1
  • adenosine deaminase, RNA-specific, B1
  • adenosine deaminase, RNA-specific, B1 L homeolog
  • adenosine deaminase, RNA-specific, B1a
  • ADARB1
  • adarb1
  • adarb1.L
  • Adarb1
  • adarb1a
Épitope
N-Term
5
4
4
2
2
1
1
1
1
Reactivité
Boeuf (Vache), Chien, Cobaye, Cheval, Humain, Souris, Lapin, Rat (Rattus), Poisson zèbre (Danio rerio)
39
31
25
3
3
2
1
1
1
1
1
1
Hôte
Lapin
31
8
4
Clonalité
Polyclonal
Conjugué
Cet anticorp RED1 est non-conjugé
1
1
1
1
1
1
1
Application
Western Blotting (WB)
35
12
10
8
4
3
2
1
1
Options
Immunogène The immunogen is a synthetic peptide directed towards the N terminal region of human ADARB1
Séquence QLSNGGGGGP GRKRPLEEGS NGHSKYRLKK RRKTPGPVLP KNALMQLNEI
Homologie Cow: 83%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%
Attributs du produit This is a rabbit polyclonal antibody against ADARB1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Plasmids, Primers & others Plasmids, Primers & others RED1 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation ADARB1 (ADARB1 Antibody Extrait)
Sujet ADARB1 is an enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site.This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.
Alias Symbols: RED1, ADAR2, DRABA2, DRADA2
Protein Interaction Partner: EBNA1BP2, IFRD2, CCDC124, NIFK, C7orf50, C1orf35, STRBP, BRIX1, SDAD1, ZFR, NOP16, MRTO4, RRS1, BMI1, APP, UBC, PPP2CB, WWP2, PIN1,
Protein Size: 701
Poids moléculaire 77 kDa
ID gène 104
NCBI Accession NM_001112, NP_001103
UniProt Q4AE79
Indications d'application Optimal working dilutions should be determined experimentally by the investigator.
Commentaires

Antigen size: 701 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freeze-thaw cycles.
Stock -20 °C
Stockage commentaire For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Images (Fournisseur)
Western Blotting (WB) image for anti-Adenosine Deaminase, RNA-Specific, B1 (ADARB1) (N-Term) antibody (ABIN2778757) WB Suggested Anti-ADARB1 Antibody Titration: 1.25ug/ml ELISA Titer: 1:1562500 Pos...
 image for anti-Adenosine Deaminase, RNA-Specific, B1 (ADARB1) (N-Term) antibody (ABIN2778757) anti-Adenosine Deaminase, RNA-Specific, B1 (ADARB1) (N-Term) antibody (Image 2)
Western Blotting (WB) image for anti-Adenosine Deaminase, RNA-Specific, B1 (ADARB1) (N-Term) antibody (ABIN2778757) ADARB1 antibody - N-terminal region validated by WB using Mouse brains at 1:1000.
Produit citée dans: Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." dans: Gene, Vol. 512, Issue 2, pp. 219-25, 2012 (PubMed).

Background publications Kawahara, Ito, Ito, Tsuji, Kwak: "Novel splice variants of human ADAR2 mRNA: skipping of the exon encoding the dsRNA-binding domains, and multiple C-terminal splice sites." dans: Gene, Vol. 363, pp. 193-201, 2005 (PubMed).

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